Innovative Technology Born from Medical-Engineering Collaboration
The Elovution of BioStealth™
The Challenge for "True Long-Term Prognosis" in the BTK Region
The lower limb, especially the BTK region, is an extremely harsh environment within the human body. It involves multi-directional mechanical loads of "extension, flexion, and torsion" associated with walking, and "biological foreign body reactions (restenosis, thrombus formation)" prone to occur due to small vessel diameter and slow blood flow. Existing stents and bioresorbable scaffolds (BRS) have challenged this issue, but none have achieved a high-level balance of "physical conformability" and "low biological irritation."
Mechanical Complexity
Leg vessels are continuously subjected to multi-directional forces different from heart vessels—"extension, flexion, and torsion"—due to walking and joint movement. In this dynamic environment, controlling physical loads and the resulting irritation to the vessel wall is a major engineering challenge for devices based on conventional design philosophies.
Biological Reaction
In the BTK region, where vessel diameter is small and blood flow velocity is slow, biological reactions on the device surface tend to be pronounced. Data showing that many cases suffer from restenosis within months even after successful initial opening with conventional balloon (PTA) treatment (reports of approx. 73% restenosis rate within 3 months) illustrates the difficulty of treating this region.
BioStealth™ New Generation Technology the Body Does Not Perceive as "Foreign": BioStealth™
BioStealth™ technology is the sum of technologies born from 20 years of dialogue between materials science and clinical medicine, aiming to harmonize with the body. Our goal is not simply to "erase" the device. By ensuring it is "not recognized as a foreign body within the body" after implantation, we fundamentally suppress the smooth muscle cell hyperproliferation that causes restenosis and draw out the blood vessel's natural healing power. This is the core of the BioStealth™ stent, which shoulders the next generation of BTK therapy.
BioDiamond™ Technology
Suppressing Metal Ion Elution by 99.9%: The Ultimate Biological Interface Harmonizing with the Vessel
Coating the stent surface with fluorine-doped diamond nano-coating (F-DLC) dramatically enhances antithrombogenicity and endothelial cell affinity. Notably, it features high barrier properties that suppress metal ion elution by 99.9%. It possesses the durability to follow without peeling even if the base material deforms significantly, maintaining "stealthiness" to the vessel intima over the long term.
BioGradia™ Technology
A Smart Drug-Control Coating That Disappears When Its Role is Complete
An active coating using biodegradable polymer. It suppresses smooth muscle cell hyperproliferation, the primary cause of restenosis, via precise drug elution over several months. Designed so that the "coating itself gradually disappears" as healing completes, leaving nothing superfluous in the vessel.
ThinForce™ Technology
Resolving the Paradox of Ultra-Thin Profile × High Radial Force: A Physical Foundation Handling Harsh Movements
A self-expanding stent design technology utilizing a special structure made of super-elastic alloy. We achieved an "Ultra-Thin Strut" design that does not impede blood flow while flexibly conforming to the large deformations unique to the BTK region. It minimizes physical load and does not hinder the natural movement of the blood vessel.
From BTK to the Lower Limbs, the Whole Body, and Artificial Organs
BioStealth™ is a revolutionary platform capable of transforming not only BTK stents but also the future of lower limb arteries, systemic vascular treatments, and "artificial organs" such as artificial hearts and valves.
